5HFA

Crystal structure of human acetylcholinesterase in complex with paraoxon and 2-PAM

5HFA の概要

• エントリーDOI: 10.2210/pdb5hfa/pdb
• 関連するPDBエントリー: 5HF5 5HF6 5HF8 5HF9
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, DIETHYL PHOSPHONATE, ... (8 entities in total)
• 機能のキーワード: acetylcholinesterase, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 121257.48

構造登録者

Franklin, M.F.,Rudolph, M.J.,Ginter, C.,Cassidy, M.S.,Cheung, J. (登録日: 2016-01-06, 公開日: 2016-06-22, 最終更新日: 2023-09-27)

• 主引用文献: Franklin, M.C.,Rudolph, M.J.,Ginter, C.,Cassidy, M.S.,Cheung, J.; Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface.; Proteins, 84:1246-1256, 2016; PubMed: 27191504; DOI: 10.1002/prot.25073

実験手法

X-RAY DIFFRACTION (2.201 Å)