5HF9
Crystal structure of human acetylcholinesterase in complex with paraoxon and HI6
Summary for 5HF9
Entry DOI | 10.2210/pdb5hf9/pdb |
Related | 5HF5 5HF6 5HF8 5HFA |
Descriptor | Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, DIETHYL PHOSPHONATE, ... (9 entities in total) |
Functional Keywords | acetylcholinesterase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 121790.02 |
Authors | Franklin, M.F.,Rudolph, M.J.,Ginter, C.,Cassidy, M.S.,Cheung, J. (deposition date: 2016-01-06, release date: 2016-06-22, Last modification date: 2023-09-27) |
Primary citation | Franklin, M.C.,Rudolph, M.J.,Ginter, C.,Cassidy, M.S.,Cheung, J. Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84:1246-1256, 2016 Cited by PubMed: 27191504DOI: 10.1002/prot.25073 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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