5HEM

Crystal structure of the N-terminus D161Y bromodomain mutant of human BRD2

Summary for 5HEM

• Entry DOI: 10.2210/pdb5hem/pdb
• Descriptor: Bromodomain-containing protein 2, 1,2-ETHANEDIOL, ACETATE ION, ... (5 entities in total)
• Functional Keywords: transcription regulation, post translational modifications recognition, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P25440
• Total number of polymer chains: 2
• Total formula weight: 30381.78

Authors

Tallant, C.,Lori, C.,Pasquo, A.,Chiaraluce, R.,Consalvi, V.,Newman, J.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S. (deposition date: 2016-01-06, release date: 2016-01-20, Last modification date: 2024-01-10)

• Primary citation: Tallant, C.,Lori, C.,Pasquo, A.,Chiaraluce, R.,Consalvi, V.,Newman, J.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.; Crystal structure of the N-terminus D161Y bromodomain mutant of human BRD2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)