5HCP
Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome
This is a non-PDB format compatible entry.
Summary for 5HCP
Entry DOI | 10.2210/pdb5hcp/pdb |
Related | 5HAU 5HCQ 5HCR 5HD1 |
Descriptor | 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (59 entities in total) |
Functional Keywords | metalnikowin, antimicrobial peptide, antibiotic, 70s ribosome, inhibition of translation, peptidyl transferase inhibitors, 50s ribosomal subunit, peptide exit tunnel, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Escherichia coli More |
Total number of polymer chains | 110 |
Total formula weight | 4466943.38 |
Authors | Gagnon, M.G.,Roy, R.N.,Lomakin, I.B.,Florin, T.,Mankin, A.S.,Steitz, T.A. (deposition date: 2016-01-04, release date: 2016-04-06, Last modification date: 2024-03-06) |
Primary citation | Gagnon, M.G.,Roy, R.N.,Lomakin, I.B.,Florin, T.,Mankin, A.S.,Steitz, T.A. Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44:2439-2450, 2016 Cited by PubMed: 26809677DOI: 10.1093/nar/gkw018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.894 Å) |
Structure validation
Download full validation report