5HCH

X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair

Summary for 5HCH

• Entry DOI: 10.2210/pdb5hch/pdb
• Related: 1OXC
• Descriptor: Fucose-binding lectin, DNA (5'-D(*CP*GP*CP*AP*TP*TP*(DF)P*TP*AP*TP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*AP*TP*AP*(DF)P*AP*AP*TP*GP*CP*G)-3'), ... (7 entities in total)
• Functional Keywords: lecb, complex, artificial dna, phenanthrene, sugar binding protein
• Biological source: Pseudomonas aeruginosa; More
• Total number of polymer chains: 3
• Total formula weight: 20099.47

Authors

Roethlisberger, P.,Istrate, A.,Marcaida Lopez, M.J.,Visini, R.,Stocker, A.,Leumann, C.J. (deposition date: 2016-01-04, release date: 2016-03-02, Last modification date: 2024-01-10)

Primary citation

Roethlisberger, P.,Istrate, A.,Marcaida Lopez, M.J.,Visini, R.,Stocker, A.,Reymond, J.L.,Leumann, C.J.
X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair.
Chem.Commun.(Camb.), 52:4749-4752, 2016

PubMed Abstract: DNA duplexes containing unnatural base-pair surrogates are attractive biomolecular nanomaterials with potentially beneficial photophysical or electronic properties. Herein we report the first X-ray structure of a duplex containing a phen-pair in the center of the double helix in a zipper like stacking arrangement.

PubMed: 26898721
DOI: 10.1039/c6cc00374e

Experimental method

X-RAY DIFFRACTION (2.9 Å)