5H9F
Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution.
Summary for 5H9F
Entry DOI | 10.2210/pdb5h9f/pdb |
Related | 5H9E |
Descriptor | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... (10 entities in total) |
Functional Keywords | crispr cascade, immune system-rna complex, immune system/rna |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 14 |
Total formula weight | 426150.75 |
Authors | Hayes, R.P.,Xiao, Y.,Ding, F.,van Erp, P.B.G.,Rajashankar, K.,Bailey, S.,Wiedenheft, B.,Ke, A. (deposition date: 2015-12-28, release date: 2016-02-17, Last modification date: 2023-09-27) |
Primary citation | Hayes, R.P.,Xiao, Y.,Ding, F.,van Erp, P.B.,Rajashankar, K.,Bailey, S.,Wiedenheft, B.,Ke, A. Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli. Nature, 530:499-503, 2016 Cited by PubMed: 26863189DOI: 10.1038/nature16995 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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