5H1E

Interaction between vitamin D receptor and coactivator peptide SRC2-3

Summary for 5H1E

Entry DOI	10.2210/pdb5h1e/pdb
Descriptor	Vitamin D3 receptor, Nuclear receptor coactivator 2 peptide, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	transcription, vitamin d3, vdre, rxr, co-factors, tif2
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	2
Total formula weight	32605.52
Authors	Egawa, D.,Itoh, T.,Kato, A.,Kataoka, S.,Anami, Y.,Yamamoto, K. (deposition date: 2016-10-08, release date: 2017-01-11, Last modification date: 2024-03-20)
Primary citation	Egawa, D.,Itoh, T.,Kato, A.,Kataoka, S.,Anami, Y.,Yamamoto, K. SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinity Bioorg. Med. Chem., 25:568-574, 2017 Cited by PubMed: 27890450 DOI: 10.1016/j.bmc.2016.11.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation