5H02
Crystal structure of Methanohalophilus portucalensis glycine sarcosine N-methyltransferase tetramutant (H21G, E23T, E24N, L28S)
5H02 の概要
エントリーDOI | 10.2210/pdb5h02/pdb |
分子名称 | Glycine sarcosine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, TRIMETHYL GLYCINE, ... (4 entities in total) |
機能のキーワード | s-adenosylmethionine-dependent methyltransferases, sam, adomet-mtase, class i monomethylation, glycine, sarcosine, rate-limiting enzyme, betaine biosynthesis, betaine-mediated feedback inhibition, transferase |
由来する生物種 | Methanohalophilus portucalensis FDF-1 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 33139.61 |
構造登録者 | |
主引用文献 | Lee, Y.R.,Lin, T.S.,Lai, S.J.,Liu, M.S.,Lai, M.C.,Chan, N.L. Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity. Sci Rep, 6:38071-38071, 2016 Cited by PubMed: 27934872DOI: 10.1038/srep38071 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.776 Å) |
構造検証レポート
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