5GZO

Structure of neutralizing antibody bound to Zika envelope protein

5GZO の概要

関連するPDBエントリー5GZN
分子名称Genome polyprotein, Antibody heavy chain, Antibody light chain (3 entities in total)
機能のキーワードzika virus, human neutralizing antibodies, envelope protein, molecular determinants, viral protein-immune system complex, viral protein/immune system
由来する生物種Zika virus (ZIKV)
詳細
細胞内の位置Virion membrane ; Multi-pass membrane protein  H9A910
ポリマー鎖数6
分子量合計182761.19
構造登録者
主引用文献
Wang, Q.,Yang, H.,Liu, X.,Dai, L.,Ma, T.,Qi, J.,Wong, G.,Peng, R.,Liu, S.,Li, J.,Li, S.,Song, J.,Liu, J.,He, J.,Yuan, H.,Xiong, Y.,Liao, Y.,Li, J.,Yang, J.,Tong, Z.,Griffin, B.D.,Bi, Y.,Liang, M.,Xu, X.,Qin, C.,Cheng, G.,Zhang, X.,Wang, P.,Qiu, X.,Kobinger, G.,Shi, Y.,Yan, J.,Gao, G.F.
Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8:369ra179-369ra179, 2016
PubMed: 27974667 (主引用文献が同じPDBエントリー)
DOI: 10.1126/scitranslmed.aai8336
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.755 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.278807.5%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード