5GWA
Crystal structure of TLA-3 extended-spectrum beta-lactamase in a complex with avibactam
Summary for 5GWA
Entry DOI | 10.2210/pdb5gwa/pdb |
Related | 5GS8 |
Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, SULFATE ION, ... (7 entities in total) |
Functional Keywords | extended-spectrum beta-lactamase, hydrolase |
Biological source | Serratia marcescens |
Total number of polymer chains | 1 |
Total formula weight | 32552.11 |
Authors | Wachino, J.,Jin, W.,Arakawa, Y. (deposition date: 2016-09-09, release date: 2017-07-12, Last modification date: 2023-11-08) |
Primary citation | Jin, W.,Wachino, J.,Yamaguchi, Y.,Kimura, K.,Kumar, A.,Yamada, M.,Morinaka, A.,Sakamaki, Y.,Yonezawa, M.,Kurosaki, H.,Arakawa, Y. Structural Insights into the TLA-3 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam and OP0595. Antimicrob. Agents Chemother., 61:-, 2017 Cited by PubMed: 28739781DOI: 10.1128/AAC.00501-17 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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