5GTD

o-Succinylbenzoate CoA Synthetase (MenE) from Bacillus Subtilis in Complex with the Acyl-adenylate Intermediate OSB-AMP

5GTD の概要

• エントリーDOI: 10.2210/pdb5gtd/pdb
• 分子名称: 2-succinylbenzoate--CoA ligase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... (8 entities in total)
• 機能のキーワード: adenylate-forming enzyme, adenylate intermdiate, osbamp, in-line backside nucleophilic substitution, strained conformation, ligase
• 由来する生物種: Bacillus subtilis (strain 168)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 112018.39

構造登録者

Chen, Y.,Guo, Z. (登録日: 2016-08-20, 公開日: 2017-01-04, 最終更新日: 2023-11-08)

• 主引用文献: Chen, Y.,Jiang, Y.,Guo, Z.; Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate; Biochemistry, 55:6685-6695, 2016; PubMed: 27933791; DOI: 10.1021/acs.biochem.6b00889

実験手法

X-RAY DIFFRACTION (2.69 Å)