5GT9

The X-ray structure of 7beta-hydroxysteroid dehydrogenase

Summary for 5GT9

• Entry DOI: 10.2210/pdb5gt9/pdb
• Descriptor: Oxidoreductase, short chain dehydrogenase/reductase family protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: short chain dehydrogenase, steroid substrates, oxidoreductase
• Biological source: Collinsella aerofaciens ATCC 25986
• Total number of polymer chains: 2
• Total formula weight: 59054.37

Authors

Wang, F.,Wang, R.,Lv, Z.,Chen, Q.,Huo, X. (deposition date: 2016-08-19, release date: 2017-05-17, Last modification date: 2023-11-08)

• Primary citation: Wang, R.,Wu, J.,Jin, D.K.,Chen, Y.,Lv, Z.,Chen, Q.,Miao, Q.,Huo, X.,Wang, F.; Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes; Acta Crystallogr F Struct Biol Commun, 73:246-252, 2017; PubMed: 28471355; DOI: 10.1107/S2053230X17004460

Experimental method

X-RAY DIFFRACTION (1.7 Å)