5GSO

Crystal Structures of EV71 3C Protease in complex with NK-1.8k

Summary for 5GSO

Entry DOI	10.2210/pdb5gso/pdb
Descriptor	3C protein, ~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]propan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide (3 entities in total)
Functional Keywords	ev71 3c protease nk-1.8k, hydrolase
Biological source	Enterovirus A71
Total number of polymer chains	5
Total formula weight	114680.77
Authors	Wang, Y. (deposition date: 2016-08-16, release date: 2017-05-31, Last modification date: 2023-11-08)
Primary citation	Wang, Y.,Cao, L.,Zhai, Y.,Yin, Z.,Sun, Y.,Shang, L. Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor Antimicrob. Agents Chemother., 61:-, 2017 Cited by PubMed: 28461310 DOI: 10.1128/AAC.00298-17 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation