5GMM
Crystal structure of human Carbonic anhydrase I in complex with polmacoxib
Summary for 5GMM
Entry DOI | 10.2210/pdb5gmm/pdb |
Related | 5GMN |
Descriptor | Carbonic anhydrase 1, ZINC ION, 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxidanylidene-furan-2-yl]benzenesulfonamide, ... (4 entities in total) |
Functional Keywords | lyase, inhibitor, complex |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 60176.92 |
Authors | Kim, H.T.,Hwang, K.Y. (deposition date: 2016-07-14, release date: 2017-05-24, Last modification date: 2023-11-08) |
Primary citation | Kim, H.T.,Cha, H.,Hwang, K.Y. Structural insight into the inhibition of carbonic anhydrase by the COX-2-selective inhibitor polmacoxib (CG100649). Biochem. Biophys. Res. Commun., 478:1-6, 2016 Cited by PubMed: 27475498DOI: 10.1016/j.bbrc.2016.07.114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.003 Å) |
Structure validation
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