5GKR
Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide
Summary for 5GKR
Entry DOI | 10.2210/pdb5gkr/pdb |
Related | 5GKS |
Descriptor | IgG2, Fab (heavy chain), lambda, Fab (light chain), DNA (5'-D(P*TP*TP*TP*T)-3'), ... (4 entities in total) |
Functional Keywords | antibody, lupus, dna, fab, immune system-dna complex, immune system/dna |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 93862.87 |
Authors | Arimori, T.,Sakakibara, S.,Kikutani, H.,Takagi, J. (deposition date: 2016-07-05, release date: 2017-07-05, Last modification date: 2023-11-08) |
Primary citation | Sakakibara, S.,Arimori, T.,Yamashita, K.,Jinzai, H.,Motooka, D.,Nakamura, S.,Li, S.,Takeda, K.,Katayama, J.,El Hussien, M.A.,Narazaki, M.,Tanaka, T.,Standley, D.M.,Takagi, J.,Kikutani, H. Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus Sci Rep, 7:16428-16428, 2017 Cited by PubMed: 29180749DOI: 10.1038/s41598-017-16681-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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