5GIX

Human serum albumin-Palmitic acid-Fe(Hn3piT)Cl2

Summary for 5GIX

• Entry DOI: 10.2210/pdb5gix/pdb
• Descriptor: Serum albumin, 14-piperidin-1-yl-11-oxa-13$l^{3}-thia-15,16$l^{4}-diaza-12$l^{3}-ferratetracyclo[8.7.0.0^{2,7}.0^{12,16}]heptadeca-1(10),2(7),3,5,8,13,16-heptaene, PALMITIC ACID, ... (4 entities in total)
• Functional Keywords: ferric compound, anticancer mechanism, tumor targeting, therapeutic effect, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted: P02768
• Total number of polymer chains: 2
• Total formula weight: 136243.28

Authors

Yang, F.,Qi, J.,Wang, T. (deposition date: 2016-06-25, release date: 2017-07-19, Last modification date: 2023-11-08)

• Primary citation: Qi, J.,Gou, Y.,Zhang, Y.,Yang, K.,Chen, S.,Liu, L.,Wu, X.,Wang, T.,Zhang, W.,Yang, F.; Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain; J. Med. Chem., 59:7497-7511, 2016; PubMed: 27441502; DOI: 10.1021/acs.jmedchem.6b00509

Experimental method

X-RAY DIFFRACTION (2.801 Å)