5GI7

Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-phenylethylamine

5GI7 の概要

• エントリーDOI: 10.2210/pdb5gi7/pdb
• 関連するPDBエントリー: 5GI5 5GI6 5GI8 5GI9
• 分子名称: Dopamine N-acetyltransferase, COENZYME A, N-(2-phenylethyl)acetamide, ... (5 entities in total)
• 機能のキーワード: dopamine n-acetyltransferase(dat), gcn5-related n-acetyltransferase(gnat), arylalkylamine n-acetyltransferase(aanat), order bi-bi sequential mechanism, transferase
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25688.25

構造登録者

Yang, Y.C.,Lin, S.J.,Cheng, K.C.,Cheng, H.C.,Lyu, P.C. (登録日: 2016-06-22, 公開日: 2017-07-05, 最終更新日: 2024-03-20)

• 主引用文献: Wu, C.Y.,Hu, I.C.,Yang, Y.C.,Ding, W.C.,Lai, C.H.,Lee, Y.Z.,Liu, Y.C.,Cheng, H.C.,Lyu, P.C.; An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase.; Commun Biol, 3:441-441, 2020; PubMed: 32796911; DOI: 10.1038/s42003-020-01177-9

実験手法

X-RAY DIFFRACTION (1.201 Å)