5GGF

Crystal structure of human protein O-mannose beta-1,2-N-acetylglucosaminyltransferase form II

Summary for 5GGF

Related5GGG 5GGI 5GGJ 5GGK 5GGL 5GGN 5GGO 5GGP
DescriptorProtein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (2 entities in total)
Functional Keywordsglycosyltransferase, o-mannosylation, alpha-dystroglycan, transferase, sugar binding protein
Biological sourceHomo sapiens (Human)
Cellular locationGolgi apparatus membrane ; Single-pass type II membrane protein  Q8WZA1
Total number of polymer chains3
Total molecular weight196654.36
Authors
Kuwabara, N.,Senda, T.,Kato, R. (deposition date: 2016-06-15, release date: 2016-08-10, Last modification date: 2016-08-31)
Primary citation
Kuwabara, N.,Manya, H.,Yamada, T.,Tateno, H.,Kanagawa, M.,Kobayashi, K.,Akasaka-Manya, K.,Hirose, Y.,Mizuno, M.,Ikeguchi, M.,Toda, T.,Hirabayashi, J.,Senda, T.,Endo, T.,Kato, R.
Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan
Proc.Natl.Acad.Sci.USA, 113:9280-9285, 2016
PubMed: 27493216 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1525545113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.49 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.253130.5%3.3%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution