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5G6U

Crystal structure of langerin carbohydrate recognition domain with GlcNS6S

Summary for 5G6U
Entry DOI10.2210/pdb5g6u/pdb
DescriptorLANGERIN, TRYPTOPHAN, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... (7 entities in total)
Functional Keywordscarbohydrate binding protein, langerin, cd207, clec4k, c-type lectins, clrs, sulfated carbohydrates
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMembrane ; Single-pass type II membrane protein : Q9UJ71
Total number of polymer chains4
Total formula weight121328.70
Authors
Porkolab, V.,Chabrol, E.,Varga, N.,Ordanini, S.,Sutkeviciute, I.,Thepaut, M.,Bernardi, A.,Fieschi, F. (deposition date: 2016-07-21, release date: 2018-02-21, Last modification date: 2024-01-10)
Primary citationPorkolab, V.,Chabrol, E.,Varga, N.,Ordanini, S.,Sutkeviciu Te, I.,Thepaut, M.,Garcia-Jimenez, M.J.,Girard, E.,Nieto, P.M.,Bernardi, A.,Fieschi, F.
Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
ACS Chem. Biol., 13:600-608, 2018
Cited by
PubMed: 29272097
DOI: 10.1021/acschembio.7b00958
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.844 Å)
Structure validation

217705

数据于2024-03-27公开中

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