5G0Q
beta-glucuronidase with an activity-based probe (N-alkyl cyclophellitol aziridine) bound
Summary for 5G0Q
Entry DOI | 10.2210/pdb5g0q/pdb |
Related | 5G0M |
Descriptor | BETA-GLUCURONIDASE, (1R,2S,3R,4S,5S,6R)-7-(8-AZIDOOCTYL)-3,4,5-TRIHYDROXY-, GLYCEROL, ... (4 entities in total) |
Functional Keywords | hydrolase, gh79, beta-glucuronidase, activity-based probe, retaining enzyme |
Biological source | ACIDOBACTERIUM CAPSULATUM |
Total number of polymer chains | 1 |
Total formula weight | 51360.16 |
Authors | Jin, Y.,Wu, L.,Jiang, J.B.,Overkleeft, H.S.,Davies, G.J. (deposition date: 2016-03-22, release date: 2017-04-12, Last modification date: 2024-01-10) |
Primary citation | Wu, L.,Jiang, J.,Jin, Y.,Kallemeijn, W.W.,Kuo, C.L.,Artola, M.,Dai, W.,van Elk, C.,van Eijk, M.,van der Marel, G.A.,Codee, J.D.C.,Florea, B.I.,Aerts, J.M.F.G.,Overkleeft, H.S.,Davies, G.J. Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13:867-873, 2017 Cited by PubMed: 28581485DOI: 10.1038/nchembio.2395 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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