5FUP
Crystal structure of human JARID1B in complex with 2-oxoglutarate.
Summary for 5FUP
Entry DOI | 10.2210/pdb5fup/pdb |
Related | 5FV3 |
Descriptor | LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ... (8 entities in total) |
Functional Keywords | oxidoreductase, jarid1b, plu1 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus : Q9UGL1 |
Total number of polymer chains | 1 |
Total formula weight | 56433.46 |
Authors | Nowak, R.,Srikannathasan, V.,Johansson, C.,Gileadi, C.,Kupinska, K.,Strain-Damerell, C.,Szykowska, A.,Talon, R.,von Delft, F.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Oppermann, U. (deposition date: 2016-01-28, release date: 2016-03-23, Last modification date: 2024-01-10) |
Primary citation | Johansson, C.,Velupillai, S.,Tumber, A.,Szykowska, A.,Hookway, E.S.,Nowak, R.P.,Strain-Damerell, C.,Gileadi, C.,Philpott, M.,Burgess-Brown, N.,Wu, N.,Kopec, J.,Nuzzi, A.,Steuber, H.,Egner, U.,Badock, V.,Munro, S.,Lathangue, N.B.,Westaway, S.,Brown, J.,Athanasou, N.,Prinjha, R.,Brennan, P.E.,Oppermann, U. Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development. Nat.Chem.Biol., 12:539-, 2016 Cited by PubMed: 27214403DOI: 10.1038/NCHEMBIO.2087 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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