5FU8
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
Summary for 5FU8
Entry DOI | 10.2210/pdb5fu8/pdb |
Descriptor | GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, N-(6-amino-1-(4-bromo-3-methylbenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzenesulfonamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | thymidylyl, transferase, allosteric, inhibitor, pseudomonas |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 4 |
Total formula weight | 137496.64 |
Authors | Alphey, M.S.,Tran, F.,Westwood, N.J.,Naismith, J.H. (deposition date: 2016-01-21, release date: 2017-02-22, Last modification date: 2024-01-10) |
Primary citation | Tran, F.,Alphey, M.S.,Westwood, N.J.,Naismith, J.H. Allosteric Competitive Inhibitors of the Glucose-1-Phosphate Thymidylyltransferase (Rmla) from Pseudomonas Aeruginosa. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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