5FR9

Structure of transaminase ATA-117 arRmut11 from Arthrobacter sp. KNK168 inhibited with 1-(4-Bromophenyl)-2-fluoroethylamine

5FR9 の概要

• エントリーDOI: 10.2210/pdb5fr9/pdb
• 分子名称: (R)-AMINE TRANSAMINASE, [4-[3-(4-bromophenyl)-3-oxidanylidene-propyl]-6-methyl-5-oxidanyl-pyridin-3-yl]methyl phosphate (3 entities in total)
• 機能のキーワード: transferase, transminase, aminotransferase, plp, inhibitor, fluoroamine
• 由来する生物種: ARTHROBACTER SP.
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 447990.83

構造登録者

Cuetos, A.,Kroutil, W.,Lavandera, I.,Grogan, G. (登録日: 2015-12-16, 公開日: 2016-03-02, 最終更新日: 2024-01-10)

• 主引用文献: Cuetos, A.,Garcia-Ramos, M.,Fischereder, E.,Diaz-Rodriguez, A.,Grogan, G.,Gotor, V.,Kroutil, W.,Lavandera, I.; Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched Beta-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination.; Angew.Chem.Int.Ed.Engl., 55:3144-, 2016; PubMed: 26836037; DOI: 10.1002/ANIE.201510554

実験手法

X-RAY DIFFRACTION (2.81 Å)