5FQC
Crystal structure of the metallo-beta-lactamase VIM-2 with 2C
Summary for 5FQC
Entry DOI | 10.2210/pdb5fqc/pdb |
Related | 5FQ9 |
Descriptor | BETA-LACTAMASE, FORMIC ACID, ZINC ION, ... (6 entities in total) |
Functional Keywords | hydrolase, antibiotic resistance |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 2 |
Total formula weight | 52755.96 |
Authors | Brem, J.,Cain, R.,McDonough, M.A.,Clifton, I.J.,Fishwick, C.W.G.,Schofield, C.J. (deposition date: 2015-12-08, release date: 2016-08-17, Last modification date: 2024-01-10) |
Primary citation | Brem, J.,Cain, R.,Cahill, S.,McDonough, M.A.,Clifton, I.J.,Jimenez-Castellanos, J.C.,Avison, M.B.,Spencer, J.,Fishwick, C.W.,Schofield, C.J. Structural basis of metallo-beta-lactamase, serine-beta-lactamase and penicillin-binding protein inhibition by cyclic boronates. Nat Commun, 7:12406-12406, 2016 Cited by PubMed: 27499424DOI: 10.1038/ncomms12406 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.449 Å) |
Structure validation
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