5FPI

Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE

Summary for 5FPI

• Entry DOI: 10.2210/pdb5fpi/pdb
• Descriptor: AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT (3 entities in total)
• Functional Keywords: endocytosis, clathrin adaptor
• Biological source: RATTUS NORVEGICUS (NORWAY RAT); More
• Cellular location: Cell membrane : P84092
• Total number of polymer chains: 2
• Total formula weight: 52053.25

Authors

Owen, D.J.,Evans, P.R.,Ivaska, J. (deposition date: 2015-11-30, release date: 2016-01-20, Last modification date: 2024-01-10)

• Primary citation: De Franceschi, N.,Arjonen, A.,Elkhatib, N.,Denessiouk, K.,Wrobel, A.G.,Wilson, T.A.,Pouwels, J.,Montagnac, G.,Owen, D.J.,Ivaska, J.; Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions; Nat.Struct.Mol.Biol., 23:172-, 2016; PubMed: 26779610; DOI: 10.1038/NSMB.3161

Experimental method

X-RAY DIFFRACTION (2.77 Å)