5FOR
Cryptic TIR
Summary for 5FOR
| Entry DOI | 10.2210/pdb5for/pdb |
| Descriptor | PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1, PENTAETHYLENE GLYCOL, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, ... (4 entities in total) |
| Functional Keywords | cell cycle, tir, immume response |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Cytoplasm : Q6ZUJ8 |
| Total number of polymer chains | 1 |
| Total formula weight | 16820.44 |
| Authors | Halabi, S.,Gay, N.J.,Moncrieffe, M.C. (deposition date: 2015-11-25, release date: 2016-12-07, Last modification date: 2017-03-01) |
| Primary citation | Halabi, S.,Sekine, E.,Verstak, B.,Gay, N.J.,Moncrieffe, M.C. Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome. J. Biol. Chem., 292:652-660, 2017 Cited by PubMed: 27909057DOI: 10.1074/jbc.M116.761528 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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