5FLX

Mammalian 40S HCV-IRES complex

Summary for 5FLX

Entry DOI	10.2210/pdb5flx/pdb
EMDB information	3221
Descriptor	18S RRNA, 40S RIBOSOMAL PROTEIN S8, 40S RIBOSOMAL PROTEIN S9, ... (37 entities in total)
Functional Keywords	ribosome, translation initiation, hepatitis c virus internal ribosome entry site
Biological source	HEPATITIS C VIRUS (HCV) More
Cellular location	Cytoplasm : P62241 P46781 P46783 P25398 P62269 P60866 P61247 P23396 Cell membrane: P08865 Nucleus : P39019 Ubiquitin: Cytoplasm : P62979 Cell membrane ; Peripheral membrane protein: P63244 Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : P62081
Total number of polymer chains	35
Total formula weight	1385962.24
Authors	Yamamoto, H.,Collier, M.,Loerke, J.,Ismer, J.,Schmidt, A.,Hilal, T.,Sprink, T.,Yamamoto, K.,Mielke, T.,Burger, J.,Shaikh, T.R.,Dabrowski, M.,Hildebrand, P.W.,Scheerer, P.,Spahn, C.M.T. (deposition date: 2015-10-28, release date: 2015-12-23, Last modification date: 2017-08-30)
Primary citation	Yamamoto, H.,Collier, M.,Loerke, J.,Ismer, J.,Schmidt, A.,Hilal, T.,Sprink, T.,Yamamoto, K.,Mielke, T.,Burger, J.,Shaikh, T.R.,Dabrowski, M.,Hildebrand, P.W.,Scheerer, P.,Spahn, C.M. Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34:3042-, 2015 Cited by PubMed: 26604301 DOI: 10.15252/EMBJ.201592469 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation