5FLT

Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination

Summary for 5FLT

• Entry DOI: 10.2210/pdb5flt/pdb
• Related: 5FLO 5FLP 5FLQ 5FLR 5FLS
• Descriptor: HUMAN CARBONIC ANHYDRASE 2, ZINC ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: lyase, fragments, carbonic anhydrase, metalloprotein
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 29660.78

Authors

Woods, L.A.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.A. (deposition date: 2015-10-28, release date: 2016-03-02, Last modification date: 2024-01-10)

• Primary citation: Woods, L.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.; Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination.; J.Med.Chem., 59:2192-, 2016; PubMed: 26882437; DOI: 10.1021/ACS.JMEDCHEM.5B01940

Experimental method

X-RAY DIFFRACTION (1.67 Å)