5FLO

Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination

Summary for 5FLO

Entry DOI	10.2210/pdb5flo/pdb
Related	5FLP 5FLQ 5FLR 5FLS 5FLT
Descriptor	CARBONIC ANHYDRASE 2, ZINC ION, 5-[(4-chloranylphenoxy)methyl]-1H-1,2,3,4-tetrazole, ... (4 entities in total)
Functional Keywords	lyase, carbonic anhydrase, metalloprotein
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	29565.09
Authors	Woods, L.A.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.A. (deposition date: 2015-10-28, release date: 2016-03-02, Last modification date: 2024-01-10)
Primary citation	Woods, L.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S. Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59:2192-, 2016 Cited by PubMed: 26882437 DOI: 10.1021/ACS.JMEDCHEM.5B01940 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation