5FLO

Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination

5FLO の概要

• エントリーDOI: 10.2210/pdb5flo/pdb
• 関連するPDBエントリー: 5FLP 5FLQ 5FLR 5FLS 5FLT
• 分子名称: CARBONIC ANHYDRASE 2, ZINC ION, 5-[(4-chloranylphenoxy)methyl]-1H-1,2,3,4-tetrazole, ... (4 entities in total)
• 機能のキーワード: lyase, carbonic anhydrase, metalloprotein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29565.09

構造登録者

Woods, L.A.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.A. (登録日: 2015-10-28, 公開日: 2016-03-02, 最終更新日: 2024-01-10)

• 主引用文献: Woods, L.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.; Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination.; J.Med.Chem., 59:2192-, 2016; PubMed: 26882437; DOI: 10.1021/ACS.JMEDCHEM.5B01940

実験手法

X-RAY DIFFRACTION (1.66 Å)