5FIV
STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR
Summary for 5FIV
Entry DOI | 10.2210/pdb5fiv/pdb |
Related PRD ID | PRD_000434 |
Descriptor | RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate (3 entities in total) |
Functional Keywords | fiv protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Feline immunodeficiency virus |
Total number of polymer chains | 1 |
Total formula weight | 13765.93 |
Authors | Li, M.,Lee, T.,Morris, G.,Laco, G.,Wong, C.,Olson, A.,Elder, J.,Wlodawer, A.,Gustchina, A. (deposition date: 1998-12-02, release date: 1998-12-09, Last modification date: 2023-12-27) |
Primary citation | Li, M.,Morris, G.M.,Lee, T.,Laco, G.S.,Wong, C.H.,Olson, A.J.,Elder, J.H.,Wlodawer, A.,Gustchina, A. Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease Proteins, 38:29-40, 2000 Cited by PubMed: 10651036DOI: 10.1002/(SICI)1097-0134(20000101)38:1<29::AID-PROT4>3.0.CO;2-N PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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