5FI3

HETEROYOHIMBINE SYNTHASE THAS1 FROM CATHARANTHUS ROSEUS - COMPLEX WITH NADP+

5FI3 の概要

• エントリーDOI: 10.2210/pdb5fi3/pdb
• 分子名称: Tetrahydroalstonine synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION, ... (5 entities in total)
• 機能のキーワード: heteroyohimbine synthase, medium chain dehydrogenase/reductase, nadp+ dependent enzyme, zinc binding site, oxidoreductase
• 由来する生物種: Catharanthus roseus (Madagascar periwinkle)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 78636.54

構造登録者

Stavrinides, A.,Tatsis, E.C.,Caputi, L.,Foureau, E.,Stevenson, C.E.M.,Lawson, D.M.,Courdavault, V.,O'Connor, S.E. (登録日: 2015-12-22, 公開日: 2016-07-27, 最終更新日: 2024-05-08)

• 主引用文献: Stavrinides, A.,Tatsis, E.C.,Caputi, L.,Foureau, E.,Stevenson, C.E.,Lawson, D.M.,Courdavault, V.,O'Connor, S.E.; Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity.; Nat Commun, 7:12116-12116, 2016; PubMed: 27418042; DOI: 10.1038/ncomms12116

実験手法

X-RAY DIFFRACTION (1.05 Å)