5FHB

Crystal Structure of Protective Ebola Virus Antibody 100

Summary for 5FHB

• Entry DOI: 10.2210/pdb5fhb/pdb
• Related: 5FHA 5FHC
• Descriptor: Antibody 100 Fab heavy chain, Antibody 100 Fab light chain, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: ig domain, fab, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47460.65

Authors

Gilman, M.S.A.,McLellan, J.S. (deposition date: 2015-12-21, release date: 2016-03-16, Last modification date: 2023-09-27)

• Primary citation: Misasi, J.,Gilman, M.S.,Kanekiyo, M.,Gui, M.,Cagigi, A.,Mulangu, S.,Corti, D.,Ledgerwood, J.E.,Lanzavecchia, A.,Cunningham, J.,Muyembe-Tamfun, J.J.,Baxa, U.,Graham, B.S.,Xiang, Y.,Sullivan, N.J.,McLellan, J.S.; Structural and molecular basis for Ebola virus neutralization by protective human antibodies.; Science, 351:1343-1346, 2016; PubMed: 26917592; DOI: 10.1126/science.aad6117

Experimental method

X-RAY DIFFRACTION (1.973 Å)