5FGH
Yeast 20S proteasome beta5-K33A mutant (propeptide expressed in trans) in complex with MG132
Summary for 5FGH
Entry DOI | 10.2210/pdb5fgh/pdb |
Related | 5CZ4 |
Related PRD ID | PRD_001210 |
Descriptor | Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (18 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, proteasome, mutant, inhibitor, binding analysis, hydrolase/hydrolase inhibitor |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) More |
Total number of polymer chains | 28 |
Total formula weight | 734136.64 |
Authors | Huber, E.M.,Groll, M. (deposition date: 2015-12-20, release date: 2016-03-23, Last modification date: 2024-01-10) |
Primary citation | Huber, E.M.,Heinemeyer, W.,Li, X.,Arendt, C.S.,Hochstrasser, M.,Groll, M. A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome. Nat Commun, 7:10900-10900, 2016 Cited by PubMed: 26964885DOI: 10.1038/ncomms10900 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)