5FF1
Two way mode of binding of antithyroid drug methimazole to mammalian heme peroxidases: Structure of the complex of lactoperoxidase with methimazole at 1.97 Angstrom resolution
Summary for 5FF1
Entry DOI | 10.2210/pdb5ff1/pdb |
Related | 4QJQ |
Descriptor | Lactoperoxidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE, ... (9 entities in total) |
Functional Keywords | inhibitor, peroxidase, oxidoreductase |
Biological source | Capra hircus (Goat) |
Total number of polymer chains | 2 |
Total formula weight | 140097.02 |
Authors | Singh, R.P.,Singh, A.,Sirohi, H.,Singh, A.K.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2015-12-17, release date: 2016-01-13, Last modification date: 2023-11-08) |
Primary citation | Singh, R.P.,Singh, A.,Sirohi, H.V.,Singh, A.K.,Kaur, P.,Sharma, S.,Singh, T.P. Dual binding mode of antithyroid drug methimazole to mammalian heme peroxidases - structural determination of the lactoperoxidase-methimazole complex at 1.97 angstrom resolution. Febs Open Bio, 6:640-650, 2016 Cited by PubMed: 27398304DOI: 10.1002/2211-5463.12051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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