5FCZ

Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with Thio-NAglucal (TNX)

5FCZ の概要

• エントリーDOI: 10.2210/pdb5fcz/pdb
• 関連するPDBエントリー: 1HP4 1HP5 1JAK 1M01 5FD0
• 分子名称: B-N-acetylhexosaminidase, 1,5-anhydro-2-deoxy-2-(ethanethioylamino)-D-arabino-hex-1-enitol, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: family 20 glycoside hydrolase, sphex, gh20, thio-nag-glucal, hexosaminidase, glycosidase inhibitor, hydrolase
• 由来する生物種: Streptomyces plicatus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56913.88

構造登録者

Vadlamani, G.,Mark, B.L. (登録日: 2015-12-15, 公開日: 2016-10-26, 最終更新日: 2023-09-27)

• 主引用文献: Santana, A.G.,Vadlamani, G.,Mark, B.L.,Withers, S.G.; N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.; Chem.Commun.(Camb.), 52:7943-7946, 2016; PubMed: 27253678; DOI: 10.1039/c6cc02520j

実験手法

X-RAY DIFFRACTION (2.45 Å)