5FBU

Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin-phosphate

Summary for 5FBU

Entry DOI	10.2210/pdb5fbu/pdb
Related	5FBS 5FBT
Descriptor	Phosphoenolpyruvate synthase, Rifampin-phosphate, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	antibiotic resistance, rifamycins, rifampin, phosphotransferase, atp grasp domain, phosphohistidine domain, structural genomics, center for structural genomics of infectious diseases, csgid, transferase-antibiotic complex, transferase/antibiotic
Biological source	Listeria monocytogenes serotype 4b str. F2365
Total number of polymer chains	1
Total formula weight	98042.28
Authors	Stogios, P.J.,Wawrzak, Z.,Skarina, T.,Yim, V.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2015-12-14, release date: 2015-12-30, Last modification date: 2023-09-27)
Primary citation	Stogios, P.J.,Cox, G.,Spanogiannopoulos, P.,Pillon, M.C.,Waglechner, N.,Skarina, T.,Koteva, K.,Guarne, A.,Savchenko, A.,Wright, G.D. Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7:11343-11343, 2016 Cited by PubMed: 27103605 DOI: 10.1038/ncomms11343 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation