5FBU

Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin-phosphate

5FBU の概要

• エントリーDOI: 10.2210/pdb5fbu/pdb
• 関連するPDBエントリー: 5FBS 5FBT
• 分子名称: Phosphoenolpyruvate synthase, Rifampin-phosphate, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: antibiotic resistance, rifamycins, rifampin, phosphotransferase, atp grasp domain, phosphohistidine domain, structural genomics, center for structural genomics of infectious diseases, csgid, transferase-antibiotic complex, transferase/antibiotic
• 由来する生物種: Listeria monocytogenes serotype 4b str. F2365
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98042.28

構造登録者

Stogios, P.J.,Wawrzak, Z.,Skarina, T.,Yim, V.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2015-12-14, 公開日: 2015-12-30, 最終更新日: 2023-09-27)

• 主引用文献: Stogios, P.J.,Cox, G.,Spanogiannopoulos, P.,Pillon, M.C.,Waglechner, N.,Skarina, T.,Koteva, K.,Guarne, A.,Savchenko, A.,Wright, G.D.; Rifampin phosphotransferase is an unusual antibiotic resistance kinase.; Nat Commun, 7:11343-11343, 2016; PubMed: 27103605; DOI: 10.1038/ncomms11343

実験手法

X-RAY DIFFRACTION (2.85 Å)