5F7X

Crystal structure of Mutant Q289L of adenosine/Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with Tubercidin

Summary for 5F7X

• Entry DOI: 10.2210/pdb5f7x/pdb
• Related: 4L5A 4L5C 4L5Y 4L6I 5F73 5F76 5F77 5F78 5F7J 5F7O
• Descriptor: Methylthioadenosine phosphorylase, '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: transferase
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 3
• Total formula weight: 106820.47

Authors

Torini, J.R.,Brandao-Neto, J.,DeMarco, R.,Pereira, H.M. (deposition date: 2015-12-08, release date: 2016-12-14, Last modification date: 2023-09-27)

• Primary citation: Torini, J.R.,Brandao-Neto, J.,DeMarco, R.,Pereira, H.D.; Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.; PLoS Negl Trop Dis, 10:e0005178-e0005178, 2016; PubMed: 27935959; DOI: 10.1371/journal.pntd.0005178

Experimental method

X-RAY DIFFRACTION (1.77 Å)