5F74
Crystal structure of ChREBP:14-3-3 complex bound with AMP
Summary for 5F74
Entry DOI | 10.2210/pdb5f74/pdb |
Descriptor | 14-3-3 protein beta/alpha, Carbohydrate-responsive element-binding protein, ADENOSINE MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | chrebp, 14-3-3, amp, allosteric, transcription |
Biological source | Mus musculus (Mouse) More |
Cellular location | Cytoplasm : Q9CQV8 Nucleus : Q8VIP2 |
Total number of polymer chains | 2 |
Total formula weight | 51121.63 |
Authors | |
Primary citation | Sato, S.,Jung, H.,Nakagawa, T.,Pawlosky, R.,Takeshima, T.,Lee, W.R.,Sakiyama, H.,Laxman, S.,Wynn, R.M.,Tu, B.P.,MacMillan, J.B.,De Brabander, J.K.,Veech, R.L.,Uyeda, K. Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR. J.Biol.Chem., 291:10515-10527, 2016 Cited by PubMed: 26984404DOI: 10.1074/jbc.M115.708982 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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