5F3T

Dengue serotype 3 RNA-dependent RNA polymerase bound to JF-31-MG46

Summary for 5F3T

Entry DOI	10.2210/pdb5f3t/pdb
Related	5F3Z 5F41
Descriptor	RNA-DEPENDENT RNA POLYMERASE, ZINC ION, 2-(4-methoxy-3-phenyl-phenyl)ethanoic acid, ... (4 entities in total)
Functional Keywords	rna-dependent rna polymerase, rdrp inhibitor, dengue, transferase
Biological source	Dengue virus 3
Total number of polymer chains	1
Total formula weight	73997.96
Authors	Noble, C.G. (deposition date: 2015-12-03, release date: 2016-02-24, Last modification date: 2024-01-10)
Primary citation	Noble, C.G.,Lim, S.P.,Arora, R.,Yokokawa, F.,Nilar, S.,Seh, C.C.,Wright, S.K.,Benson, T.E.,Smith, P.W.,Shi, P.Y. A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening. J.Biol.Chem., 291:8541-8548, 2016 Cited by PubMed: 26872970 DOI: 10.1074/jbc.M115.710731 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation