5F34

Crystal structure of membrane associated PatA from Mycobacterium smegmatis in complex with S-hexadecyl Coenzyme A - P21 space group

5F34 の概要

• エントリーDOI: 10.2210/pdb5f34/pdb
• 分子名称: Phosphatidylinositol mannoside acyltransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{S})-4-[[3-(2-hexadecylsulfanylethylamino)-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate (3 entities in total)
• 機能のキーワード: acyltransferase, glycolipid biosynthesis, transferase
• 由来する生物種: Mycobacterium smegmatis str. MC2 155
• 細胞内の位置: Cell membrane ; Single-pass membrane protein : A0QWG5
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 141162.85

構造登録者

Albesa-Jove, D.,Svetlikova, Z.,Carreras-Gonzalez, A.,Tersa, M.,Sancho-Vaello, E.,Cifuente, J.O.,Mikusova, K.,Guerin, M.E. (登録日: 2015-12-02, 公開日: 2016-03-09, 最終更新日: 2024-01-10)

• 主引用文献: Albesa-Jove, D.,Svetlikova, Z.,Tersa, M.,Sancho-Vaello, E.,Carreras-Gonzalez, A.,Bonnet, P.,Arrasate, P.,Eguskiza, A.,Angala, S.K.,Cifuente, J.O.,Kordulakova, J.,Jackson, M.,Mikusova, K.,Guerin, M.E.; Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.; Nat Commun, 7:10906-10906, 2016; PubMed: 26965057; DOI: 10.1038/ncomms10906

実験手法

X-RAY DIFFRACTION (3.281 Å)