5F1W

Crystal structure of the enantiomer of a macrocyclic peptide containing fragments from alpha synuclein 36-55

Summary for 5F1W

• Entry DOI: 10.2210/pdb5f1w/pdb
• Related: 5F1T
• Descriptor: Macrocyclic peptide, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: beta-hairpins, immune system
• Biological source: synthetic construct
• Total number of polymer chains: 6
• Total formula weight: 10681.24

Authors

Salveson, P.J.,Spencer, R.K.,Nowick, J.S. (deposition date: 2015-11-30, release date: 2016-03-16, Last modification date: 2023-11-15)

• Primary citation: Salveson, P.J.,Spencer, R.K.,Nowick, J.S.; X-ray Crystallographic Structure of Oligomers Formed by a Toxic beta-Hairpin Derived from alpha-Synuclein: Trimers and Higher-Order Oligomers.; J.Am.Chem.Soc., 138:4458-4467, 2016; PubMed: 26926877; DOI: 10.1021/jacs.5b13261

Experimental method

X-RAY DIFFRACTION (2.161 Å)