5EZR

Crystal Structure of PVX_084705 bound to compound

Summary for 5EZR

• Entry DOI: 10.2210/pdb5ezr/pdb
• Related: 5F0A
• Descriptor: cGMP-dependent protein kinase, putative, N-[5-(3-{2-[(cyclopropylmethyl)amino]pyrimidin-4-yl}-7-[(dimethylamino)methyl]-6-methylimidazo[1,2-a]pyridin-2-yl)-2-fluorophenyl]methanesulfonamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: protein kinase, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Plasmodium vivax (strain Salvador I)
• Total number of polymer chains: 1
• Total formula weight: 97228.68

Authors

El Bakkouri, M.,Amani, M.,Walker, J.R.,Osborne, S.,Large, J.M.,Birchall, K.,Bouloc, N.,Smiljanic-Hurley, E.,Wheldon, M.,Harding, D.J.,Merritt, A.T.,Ansell, K.H.,Coombs, P.J.,Kettleborough, C.A.,Stewart, B.L.,Bowyer, P.W.,Gutteridge, W.E.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Baker, D.A.,Hui, R.,Loppnau, P.,Structural Genomics Consortium (SGC) (deposition date: 2015-11-26, release date: 2017-05-10, Last modification date: 2023-09-27)

• Primary citation: El Bakkouri, M.,Amani, M.,Walker, J.R.,Osborne, S.,Large, J.M.,Birchall, K.,Bouloc, N.,Smiljanic-Hurley, E.,Wheldon, M.,Harding, D.J.,Merritt, A.T.,Ansell, K.H.,Coombs, P.J.,Kettleborough, C.A.,Stewart, B.L.,Bowyer, P.W.,Gutteridge, W.E.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Baker, D.A.,Hui, R.,Loppnau, P.; Crystal Structure of PVX_084705 bound to compound; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)