5EZP
Human transthyretin (TTR) complexed with 4-hydroxy-chalcone
Summary for 5EZP
Entry DOI | 10.2210/pdb5ezp/pdb |
Related | 4I89 4PM1 4PMF 4WNS 5AKS |
Descriptor | Transthyretin, 4-hydroxy-chalcone, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | human transthyretin (ttr), chalcone, inhibitor complex, new crystal polymorph, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 8 |
Total formula weight | 108094.82 |
Authors | Polsinelli, I.,Nencetti, S.,Shepard, W.E.,Orlandini, E.,Stura, E.A. (deposition date: 2015-11-26, release date: 2016-01-27, Last modification date: 2024-01-10) |
Primary citation | Polsinelli, I.,Nencetti, S.,Shepard, W.,Ciccone, L.,Orlandini, E.,Stura, E.A. A new crystal form of human transthyretin obtained with a curcumin derived ligand. J.Struct.Biol., 194:8-17, 2016 Cited by PubMed: 26796656DOI: 10.1016/j.jsb.2016.01.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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