5EX0

Crystal structure of human SMYD3 in complex with a MAP3K2 peptide

Summary for 5EX0

• Entry DOI: 10.2210/pdb5ex0/pdb
• Related: 5EX3
• Descriptor: Histone-lysine N-methyltransferase SMYD3, MAP3K2 peptide, ZINC ION, ... (6 entities in total)
• Functional Keywords: set domain, methylation, chromatin, cancer, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : Q9H7B4
• Total number of polymer chains: 2
• Total formula weight: 51327.44

Authors

Fu, W.,Liu, N.,Qiao, Q.,Wang, M.,Min, J.,Zhu, B.,Xu, R.M.,Yang, N. (deposition date: 2015-11-23, release date: 2016-03-09, Last modification date: 2023-11-08)

• Primary citation: Fu, W.,Liu, N.,Qiao, Q.,Wang, M.,Min, J.,Zhu, B.,Xu, R.M.,Yang, N.; Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase; J.Biol.Chem., 291:9173-9180, 2016; PubMed: 26929412; DOI: 10.1074/jbc.M115.709832

Experimental method

X-RAY DIFFRACTION (2.7 Å)