5EVM

Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State

Summary for 5EVM

Entry DOI	10.2210/pdb5evm/pdb
Descriptor	Fusion glycoprotein F0, alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	fusion protein, nipah, prefusion, paramyxovirus, henipavirus, viral protein
Biological source	Nipah virus
Total number of polymer chains	6
Total formula weight	362586.58
Authors	Xu, K.,Nikolov, D.B. (deposition date: 2015-11-20, release date: 2015-12-16, Last modification date: 2023-09-27)
Primary citation	Xu, K.,Chan, Y.P.,Bradel-Tretheway, B.,Akyol-Ataman, Z.,Zhu, Y.,Dutta, S.,Yan, L.,Feng, Y.,Wang, L.F.,Skiniotis, G.,Lee, B.,Zhou, Z.H.,Broder, C.C.,Aguilar, H.C.,Nikolov, D.B. Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. Plos Pathog., 11:e1005322-e1005322, 2015 Cited by PubMed: 26646856 DOI: 10.1371/journal.ppat.1005322 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.367 Å)

Structure validation