Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5EVA

Crystal structure of the human BRPF1 bromodomain in complex with SEED16

Summary for 5EVA
Entry DOI10.2210/pdb5eva/pdb
Related5C7N
DescriptorPeregrin, ~{N}-[2,4-bis(fluoranyl)phenyl]-2-methyl-pyrazole-3-carboxamide, NITRATE ION, ... (4 entities in total)
Functional Keywordsbromodomain and phd finger-containing protein 1(brpf1), monocytic leukemia zinc-finger (moz), inhibitor, transcription, dna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : P55201
Total number of polymer chains1
Total formula weight14002.91
Authors
Zhu, J.,Caflisch, A. (deposition date: 2015-11-19, release date: 2016-06-08, Last modification date: 2024-01-10)
Primary citationZhu, J.,Caflisch, A.
Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59:5555-5561, 2016
Cited by
PubMed: 27167503
DOI: 10.1021/acs.jmedchem.6b00215
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.45 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon