5EU8
Structure of FIPV main protease in complex with dual inhibitors
Summary for 5EU8
Entry DOI | 10.2210/pdb5eu8/pdb |
Related PRD ID | PRD_002214 |
Descriptor | main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, ZINC ION, ... (5 entities in total) |
Functional Keywords | fipv, main protease, dual inhibitors, zinc, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Feline infectious peritonitis virus (FIPV) More |
Total number of polymer chains | 2 |
Total formula weight | 34305.15 |
Authors | |
Primary citation | Wang, F.,Chen, C.,Liu, X.,Yang, K.,Xu, X.,Yang, H. Crystal Structure of Feline Infectious Peritonitis Virus Main Protease in Complex with Synergetic Dual Inhibitors J.Virol., 90:1910-1917, 2015 Cited by PubMed: 26656689DOI: 10.1128/JVI.02685-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.447 Å) |
Structure validation
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