5ET8

Human muscle fructose-1,6-bisphosphatase in active R-state in complex with fructose-6-phosphate

Summary for 5ET8

• Entry DOI: 10.2210/pdb5et8/pdb
• Related: 3IFA 3IFC 4HE0 4HE1 4HE2
• Descriptor: Fructose-1,6-bisphosphatase isozyme 2, 6-O-phosphono-beta-D-fructofuranose (3 entities in total)
• Functional Keywords: hydrolase, carbohydrate metabolism, glyconeogenesis, muscle, fbpase, r-state, leucine lock, asp187, fructose-6-phosphate
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 36927.03

Authors

Barciszewski, J.,Wisniewski, J.,Kolodziejczyk, R.,Dzugaj, A.,Jaskolski, M.,Rakus, D. (deposition date: 2015-11-17, release date: 2016-11-23, Last modification date: 2024-01-10)

• Primary citation: Barciszewski, J.,Wisniewski, J.,Kolodziejczyk, R.,Dzugaj, A.,Jaskolski, M.,Rakus, D.; T-to-R switch of muscle FBPase involves extreme changes of secondary and quaternary structure; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.92 Å)